NFκB and Kidney Injury

Acute kidney injury and chronic kidney disease.

Kidney Injury

Berberine Ameliorates Chronic Kidney Injury Caused by Atherosclerotic Renovascular Disease through the Suppression of NFκB Signaling Pathway in Rats

BACKGROUND AND OBJECTIVES Impaired renal function in atherosclerotic renovascular disease (ARD) may be the result of crosstalk between atherosclerotic renovascular stenosis and amplified oxidative stress, inflammation and fibrosis. Berberine (BBR) regulates cholesterol metabolism and exerts antioxidant effects. Accordingly, we hypothesized that BBR treatment may ameliorate ARD-induced kidney in...

Rhabdomyolysis and acute kidney injury.

From the Muscle Research Unit, Depart­ ment of Internal Medicine (X.B., J.M.G.), and the Department of Nephrology (E.P.), Hospital Clínic, Institut d’Investigacions Biomèdiques August Pi i Sunyer, Univer­ sity of Barcelona, Barcelona. Address re­ print requests to Dr. Grau at the Muscle Research Unit, Department of Internal Medicine, Hospital Clínic, Institut d’Inves­ tigacions Biomèdiques Augu...

Diphenhydramine and acute kidney injury.

Seldom considered to be a drug that causes renal problems, diphenhydramine can have adverse effects in some patients, as illustrated by a case study of a middle-aged veteran. Extra precautions are urged before this medication is prescribed, especially in elderly patients.